8QUD: Cryo-EM Structure of Human Kv3.1 in Complex with Modulator AUT5

PDB ID: 8QUDDownload
MMDB ID: 244934
PDB Deposition Date: 2023/10/16
Updated in MMDB: 2024/04
Experimental Method:
electron microscopy
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 8QUD: tetrameric; determined by author and by software (PISA)
Molecular Components in 8QUD
Label Count Molecule
Proteins (4 molecules)
4
Potassium Voltage-gated Channel Subfamily C Member 1
(Gene symbol: KCNC1)
Molecule annotation
Chemicals and Non-standard biopolymers (22 molecules)
1
4
(5R)-5-ethyl-3-(6-spiro[2H-1-benzofuran-3,1'-cyclopropane]-4-yloxypyridin-3-yl)imidazolidine-2,4-dione(5R)-5-ethyl-3-(6-spiro[2H-1-benzofuran-3,1'-cyclopropane]-4-yloxypyridin-3-yl)imidazolidine-2,4-dione
2
4
ZINC IONZINC ION
3
4
CHOLESTEROL HEMISUCCINATECHOLESTEROL HEMISUCCINATE
4
4
1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE
5
6
POTASSIUM IONPOTASSIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303