8QTU: Crystal structure of human Sirt2 in complex with the super-slow substrate TNFn-3 and NAD+

PDB ID: 8QTUDownload
MMDB ID: 253884
PDB Deposition Date: 2023/10/13
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 8QTU: dimeric; determined by author and by software (PISA)
Molecular Components in 8QTU
Label Count Molecule
Proteins (2 molecules)
1
Nad-dependent Protein Deacetylase Sirtuin-2
(Gene symbol: SIRT2)
Molecule annotation
1
Peptide-based Super-slow Substrate Tnfn-3
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
ZINC IONZINC ION
2
1
NICOTINAMIDE-ADENINE-DINUCLEOTIDENICOTINAMIDE-ADENINE-DINUCLEOTIDE
3
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
1
3-dodecylsulfanyl-3-methyl-butanoic acid3-dodecylsulfanyl-3-methyl-butanoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303