8QQ6: CRYSTAL STRUCTURE OF FVIIA IN COMPLEX WITH A BENZAMIDINE-BASED INHIBITOR

PDB ID: 8QQ6Download
MMDB ID: 253551
PDB Deposition Date: 2023/10/3
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 1.87  Å
Source Organism:
Similar Structures:
Biological Unit for 8QQ6: trimeric; determined by author
Molecular Components in 8QQ6
Label Count Molecule
Proteins (3 molecules)
1
Factor VII Light Chain
(Gene symbol: F7)
Molecule annotation
1
Coagulation Factor VII
(Gene symbol: F7)
Molecule annotation
1
Tissue Factor
(Gene symbol: F3)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
2
CALCIUM IONCALCIUM ION
2
1
MAGNESIUM IONMAGNESIUM ION
3
1
alpha-D-glucopyranosealpha-D-glucopyranose
4
1
alpha-L-fucopyranosealpha-L-fucopyranose
5
2
CHLORIDE IONCHLORIDE ION
6
1
2-azanyl-~{N}-[[2-[2-[[3-methoxy-4-(1,3-oxazol-5-yl)phenyl]amino]-1,3-oxazol-5-yl]phenyl]methyl]-~{N}-methyl-ethanamide2-azanyl-~{N}-[[2-[2-[[3-methoxy-4-(1,3-oxazol-5-yl)phenyl]amino]-1,3-oxazol-5-yl]phenyl]methyl]-~{N}-methyl-ethanamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303