8QOF: Cryo-EM structure of the yeast SPT-Orm2-Dimer complex

PDB ID: 8QOFDownload
MMDB ID: 251675
PDB Deposition Date: 2023/9/28
Updated in MMDB: 2024/09
Experimental Method:
electron microscopy
Resolution: 3.3  Å
Source Organism:
Similar Structures:
Biological Unit for 8QOF: octameric; determined by author
Molecular Components in 8QOF
Label Count Molecule
Proteins (8 molecules)
2
Serine Palmitoyltransferase 1
(Gene symbol: LCB1)
Molecule annotation
2
Serine Palmitoyltransferase-regulating Protein Tsc3
(Gene symbol: TSC3)
Molecule annotation
2
Orm2 Isoform 1
Molecule annotation
2
Serine Palmitoyltransferase 2
(Gene symbol: LCB2)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
~{N}-[(2~{S},3~{S},4~{R})-1,3,4-tris(oxidanyl)octadecan-2-yl]heptacosanamide~{N}-[(2~{S},3~{S},4~{R})-1,3,4-tris(oxidanyl)octadecan-2-yl]heptacosanamide
2
2
PYRIDOXAL-5'-PHOSPHATEPYRIDOXAL-5'-PHOSPHATE
3
2
2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303