8QNZ: OXA-48 with carbamylated Lys73 in complex with hydrolysed Imipenem and bromide ion competing for binding with Arg250 at neutral pH

PDB ID: 8QNZDownload
MMDB ID: 238293
PDB Deposition Date: 2023/9/27
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.53  Å
Source Organism:
Similar Structures:
Biological Unit for 8QNZ: tetrameric; determined by author and by software (PISA)
Molecular Components in 8QNZ
Label Count Molecule
Proteins (4 molecules)
4
Beta-lactamase
(Gene symbol: bla)
Molecule annotation
Chemicals and Non-standard biopolymers (15 molecules)
1
3
(2R)-2-[(2S,3R)-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-(2-methanimidamidoethylsulfanyl)-2,3-dihydro-1H-pyrrole -5-carboxylic acid(2R)-2-[(2S,3R)-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-(2-methanimidamidoethylsulfanyl)-2,3-dihydro-1H-pyrrole -5-carboxylic acid
2
11
BROMIDE IONBROMIDE ION
3
1
1-BUTANOL1-BUTANOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303