8QLT: Human MST3 (STK24) kinase in complex with inhibitor MR30

PDB ID: 8QLTDownload
MMDB ID: 238291
PDB Deposition Date: 2023/9/20
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.47  Å
Source Organism:
Similar Structures:
Biological Unit for 8QLT: monomeric; determined by author and by software (PISA)
Molecular Components in 8QLT
Label Count Molecule
Protein (1 molecule)
1
Serine/threonine-protein Kinase 24
(Gene symbol: STK24)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
8-(4-azanylbutyl)-6-[2-chloranyl-4-(6-methylpyridin-2-yl)phenyl]-2-[3-(2-oxidanylidenepyrrolidin-1-yl)propylamino]pyrido[2,3-d]pyrimidin-7-one8-(4-azanylbutyl)-6-[2-chloranyl-4-(6-methylpyridin-2-yl)phenyl]-2-[3-(2-oxidanylidenepyrrolidin-1-yl)propylamino]pyrido[2,3-d]pyrimidin-7-one
2
3
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303