8QLR: Human MST3 (STK24) kinase in complex with inhibitor MR24

PDB ID: 8QLRDownload
MMDB ID: 238289
PDB Deposition Date: 2023/9/20
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.85  Å
Source Organism:
Similar Structures:
Biological Unit for 8QLR: dimeric; determined by author
Molecular Components in 8QLR
Label Count Molecule
Proteins (2 molecules)
2
Serine/threonine-protein Kinase 24
(Gene symbol: STK24)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
2
8-(4-azanylbutyl)-2-[1,3-bis(oxidanyl)propan-2-ylamino]-6-[2-chloranyl-4-(6-methylpyridin-2-yl)phenyl]pyrido[2,3-d]pyrimidin-7-one8-(4-azanylbutyl)-2-[1,3-bis(oxidanyl)propan-2-ylamino]-6-[2-chloranyl-4-(6-methylpyridin-2-yl)phenyl]pyrido[2,3-d]pyrimidin-7-one
2
3
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303