8QE1: Crystal structure of human MAT2a bound to S-Adenosylmethionine and Compound 15

PDB ID: 8QE1Download
MMDB ID: 244309
PDB Deposition Date: 2023/8/30
Updated in MMDB: 2024/04
Experimental Method:
x-ray diffraction
Resolution: 1.095  Å
Source Organism:
Similar Structures:
Biological Unit for 8QE1: dimeric; determined by author and by software (PISA)
Molecular Components in 8QE1
Label Count Molecule
Proteins (2 molecules)
2
S-adenosylmethionine Synthase Isoform Type-2
(Gene symbol: MAT2A)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
4-[4-[bis(fluoranyl)methoxy]phenyl]-3-cyclopropyl-6-(4-methoxyphenyl)-2~{H}-pyrazolo[4,3-b]pyridin-5-one4-[4-[bis(fluoranyl)methoxy]phenyl]-3-cyclopropyl-6-(4-methoxyphenyl)-2~{H}-pyrazolo[4,3-b]pyridin-5-one
2
2
S-ADENOSYLMETHIONINES-ADENOSYLMETHIONINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303