8QA4: MTHFR + SAH symmetric dis-inhibited state

PDB ID: 8QA4Download
MMDB ID: 238280
PDB Deposition Date: 2023/8/22
Updated in MMDB: 2025/12
Experimental Method:
electron microscopy
Resolution: 2.8  Å
Source Organism:
Similar Structures:
Biological Unit for 8QA4: dimeric; determined by author and by software
Molecular Components in 8QA4
Label Count Molecule
Proteins (2 molecules)
2
Methylenetetrahydrofolate Reductase (Nadph)
(Gene symbol: MTHFR)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
S-ADENOSYL-L-HOMOCYSTEINES-ADENOSYL-L-HOMOCYSTEINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303