8Q71: Crystal structure of SARS-CoV-2 main protease (MPro) in complex with the inhibitor GC-67

PDB ID: 8Q71Download
MMDB ID: 239472
PDB Deposition Date: 2023/8/15
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.322  Å
Source Organism:
Similar Structures:
Biological Unit for 8Q71: dimeric; determined by author and by software (PISA)
Molecular Components in 8Q71
Label Count Molecule
Proteins (2 molecules)
2
3c-like Proteinase Nsp5
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
(2~{S})-1-(3,4-dichlorophenyl)-4-(4-methoxypyridin-3-yl)carbonyl-~{N}-(thiophen-2-ylmethyl)piperazine-2-carboxamide(2~{S})-1-(3,4-dichlorophenyl)-4-(4-methoxypyridin-3-yl)carbonyl-~{N}-(thiophen-2-ylmethyl)piperazine-2-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303