8Q6F: HUMAN PI4KIIIB IN COMPLEX WITH COVALENTLY BOUND INHIBITOR (COMPOUND 4)

PDB ID: 8Q6FDownload
MMDB ID: 239812
PDB Deposition Date: 2023/8/11
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.506  Å
Source Organism:
Similar Structures:
Biological Unit for 8Q6F: monomeric; determined by author and by software (PISA)
Molecular Components in 8Q6F
Label Count Molecule
Protein (1 molecule)
1
Phosphatidylinositol 4-kinase Beta
(Gene symbol: PI4KB)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
1
3-(3-fluorosulfonyloxy-4-methoxy-phenyl)-2,5-dimethyl-7-(pyridin-4-ylmethylamino)pyrazolo[1,5-a]pyrimidine3-(3-fluorosulfonyloxy-4-methoxy-phenyl)-2,5-dimethyl-7-(pyridin-4-ylmethylamino)pyrazolo[1,5-a]pyrimidine
2
1
MAGNESIUM IONMAGNESIUM ION
3
7
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303