8Q6E: Aerobic crystal structure of HIF prolyl hydroxylase 2 (PHD2 181-407) in complex with Fe(III), 2-oxoglutarate (2OG) and HIF2alpha-CODD peptide

PDB ID: 8Q6EDownload
MMDB ID: 251236
PDB Deposition Date: 2023/8/11
Updated in MMDB: 2024/08
Experimental Method:
x-ray diffraction
Resolution: 1.37  Å
Source Organism:
Similar Structures:
Biological Unit for 8Q6E: dimeric; determined by author and by software (PISA)
Molecular Components in 8Q6E
Label Count Molecule
Proteins (2 molecules)
1
EGL Nine Homolog 1
(Gene symbol: EGLN1)
Molecule annotation
1
Endothelial PAS Domain-containing Protein 1
(Gene symbol: EPAS1)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
3
MAGNESIUM IONMAGNESIUM ION
2
2
CHLORIDE IONCHLORIDE ION
3
1
FE (III) IONFE (III) ION
4
1
2-OXOGLUTARIC ACID2-OXOGLUTARIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303