8Q68: Crystal structure of TEAD1-YBD in complex with irreversible compound SWTX-143

PDB ID: 8Q68Download
MMDB ID: 236466
PDB Deposition Date: 2023/8/11
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.58  Å
Source Organism:
Similar Structures:
Biological Unit for 8Q68: dimeric; determined by author and by software (PISA)
Molecular Components in 8Q68
Label Count Molecule
Proteins (2 molecules)
2
Transcriptional Enhancer Factor Tef-1
(Gene symbol: TEAD1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
~{N}-[(3~{S})-5-azanyl-1-[4-(trifluoromethyl)phenyl]-3,4-dihydro-2~{H}-quinolin-3-yl]propanamide~{N}-[(3~{S})-5-azanyl-1-[4-(trifluoromethyl)phenyl]-3,4-dihydro-2~{H}-quinolin-3-yl]propanamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303