8Q47: Inward-facing, open1 proteoliposome complex I at 2.9 A. Initially purified in LMNG

PDB ID: 8Q47Download
MMDB ID: 247890
PDB Deposition Date: 2023/8/5
Updated in MMDB: 2024/07
Experimental Method:
electron microscopy
Resolution: 2.9  Å
Source Organism:
Similar Structures:
Biological Unit for 8Q47: 45-meric; determined by author and by software
Molecular Components in 8Q47
Label Count Molecule
Proteins (45 molecules)
1
Nadh-ubiquinone Oxidoreductase Chain 3
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] Iron-sulfur Protein 7, Mitochondrial
(Gene symbol: NDUFS7)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] Iron-sulfur Protein 3, Mitochondrial
(Gene symbol: NDUFS3)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] Iron-sulfur Protein 2, Mitochondrial
(Gene symbol: NDUFS2)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] Flavoprotein 2, Mitochondrial
(Gene symbol: NDUFV2)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] Flavoprotein 1, Mitochondrial
(Gene symbol: NDUFV1)
Molecule annotation
1
Nadh-ubiquinone Oxidoreductase 75 KDA Subunit, Mitochondrial
(Gene symbol: NDUFS1)
Molecule annotation
1
Nadh-ubiquinone Oxidoreductase Chain 1
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] Iron-sulfur Protein 8, Mitochondrial
(Gene symbol: NDUFS8)
Molecule annotation
1
Nadh-ubiquinone Oxidoreductase Chain 6
(Gene symbol: ND6)
Molecule annotation
1
Nadh-ubiquinone Oxidoreductase Chain 4L
(Gene symbol: ND4L)
Molecule annotation
1
Nadh-ubiquinone Oxidoreductase Chain 5
Molecule annotation
1
Nadh-ubiquinone Oxidoreductase Chain 4
(Gene symbol: ND4)
Molecule annotation
1
Nadh-ubiquinone Oxidoreductase Chain 2
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] 1 Alpha Subcomplex Subunit 10, Mitochondrial
(Gene symbol: NDUFA10)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] 1 Alpha Subcomplex Subunit 9, Mitochondrial
(Gene symbol: NDUFA9)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] Iron-sulfur Protein 4, Mitochondrial
(Gene symbol: NDUFS4)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] Iron-sulfur Protein 6, Mitochondrial
(Gene symbol: NDUFS6)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] 1 Alpha Subcomplex Subunit 2
(Gene symbol: NDUFA2)
Molecule annotation
2
Acyl Carrier Protein, Mitochondrial
(Gene symbol: NDUFAB1)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] 1 Alpha Subcomplex Subunit 5
(Gene symbol: NDUFA5)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] 1 Alpha Subcomplex Subunit 6
(Gene symbol: NDUFA6)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] 1 Alpha Subcomplex Subunit 8
(Gene symbol: NDUFA8)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] 1 Alpha Subcomplex Subunit 11
(Gene symbol: NDUFA11)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] 1 Alpha Subcomplex Subunit 13
(Gene symbol: NDUFA13)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] 1 Alpha Subcomplex Subunit 1
(Gene symbol: NDUFA1)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] 1 Alpha Subcomplex Subunit 3
(Gene symbol: NDUFA3)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] 1 Subunit C1, Mitochondrial
(Gene symbol: NDUFC1)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] 1 Subunit C2
(Gene symbol: NDUFC2)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] Iron-sulfur Protein 5
(Gene symbol: NDUFS5)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] 1 Beta Subcomplex Subunit 1
(Gene symbol: NDUFB1)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] 1 Beta Subcomplex Subunit 11, Mitochondrial
(Gene symbol: NDUFB11)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] 1 Beta Subcomplex Subunit 5, Mitochondrial
(Gene symbol: NDUFB5)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] 1 Beta Subcomplex Subunit 6
(Gene symbol: NDUFB6)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] 1 Beta Subcomplex Subunit 2, Mitochondrial
(Gene symbol: NDUFB2)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] 1 Beta Subcomplex Subunit 3
(Gene symbol: NDUFB3)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] 1 Beta Subcomplex Subunit 8, Mitochondrial
(Gene symbol: NDUFB8)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] 1 Beta Subcomplex Subunit 4
(Gene symbol: NDUFB4)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] 1 Beta Subcomplex Subunit 9
(Gene symbol: NDUFB9)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] 1 Beta Subcomplex Subunit 7
(Gene symbol: NDUFB7)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] 1 Beta Subcomplex Subunit 10
(Gene symbol: NDUFB10)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] 1 Alpha Subcomplex Subunit 12
(Gene symbol: NDUFA12)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] 1 Alpha Subcomplex Subunit 7
(Gene symbol: NDUFA7)
Molecule annotation
1
Nadh Dehydrogenase [ubiquinone] Flavoprotein 3, Mitochondrial
(Gene symbol: NDUFV3)
Molecule annotation
Chemicals and Non-standard biopolymers (74 molecules)
1
15
1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE
2
26
1,2-Distearoyl-sn-glycerophosphoethanolamine1,2-Distearoyl-sn-glycerophosphoethanolamine
3
6
IRON/SULFUR CLUSTERIRON/SULFUR CLUSTER
4
5
DIUNDECYL PHOSPHATIDYL CHOLINEDIUNDECYL PHOSPHATIDYL CHOLINE
5
2
FE2/S2 (INORGANIC) CLUSTERFE2/S2 (INORGANIC) CLUSTER
6
1
FLAVIN MONONUCLEOTIDEFLAVIN MONONUCLEOTIDE
7
1
POTASSIUM IONPOTASSIUM ION
8
1
UBIQUINONE-10UBIQUINONE-10
9
8
CARDIOLIPINCARDIOLIPIN
10
2
ZINC IONZINC ION
11
1
2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE
12
1
MAGNESIUM IONMAGNESIUM ION
13
1
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
14
2
~{S}-[2-[3-[[(2~{R})-3,3-dimethyl-2-oxidanyl-4-phosphonooxy-butanoyl]amino]propanoylamino]ethyl] (3~{S})-3-oxidanyltetradecanethioate~{S}-[2-[3-[[(2~{R})-3,3-dimethyl-2-oxidanyl-4-phosphonooxy-butanoyl]amino]propanoylamino]ethyl] (3~{S})-3-oxidanyltetradecanethioate
15
1
CHOLIC ACIDCHOLIC ACID
16
1
MYRISTIC ACIDMYRISTIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303