8Q1Z: Crystal Structure of Human Vaccinia-related kinase 2 (VRK-2) bound to JA-296

PDB ID: 8Q1ZDownload
MMDB ID: 234354
PDB Deposition Date: 2023/8/1
Updated in MMDB: 2023/08
Experimental Method:
x-ray diffraction
Resolution: 1.85  Å
Source Organism:
Similar Structures:
Biological Unit for 8Q1Z: monomeric; determined by author and by software
Molecular Components in 8Q1Z
Label Count Molecule
Protein (1 molecule)
1
Serine/threonine-protein Kinase Vrk2
(Gene symbol: VRK2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
2-[4-[[4-[(3-~{tert}-butyl-1~{H}-pyrazol-5-yl)amino]pyrimidin-2-yl]amino]phenyl]ethanenitrile2-[4-[[4-[(3-~{tert}-butyl-1~{H}-pyrazol-5-yl)amino]pyrimidin-2-yl]amino]phenyl]ethanenitrile
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303