8Q1X: Structural analysis of PLD3 reveals insights into the mechanism of lysosomal 5' exonuclease-mediated nucleic acid degradation

PDB ID: 8Q1XDownload
MMDB ID: 239443
PDB Deposition Date: 2023/8/1
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.85  Å
Source Organism:
Similar Structures:
Biological Unit for 8Q1X: dimeric; determined by author and by software (PISA)
Molecular Components in 8Q1X
Label Count Molecule
Proteins (2 molecules)
2
5'-3' Exonuclease Pld3
(Gene symbol: PLD3)
Molecule annotation
Chemicals and Non-standard biopolymers (46 molecules)
1
8
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
8
alpha-D-mannopyranosealpha-D-mannopyranose
3
4
THYMIDINE-5'-THIOPHOSPHATETHYMIDINE-5'-THIOPHOSPHATE
4
3
PHOSPHATE IONPHOSPHATE ION
5
15
1,2-ETHANEDIOL1,2-ETHANEDIOL
6
2
MANGANESE (II) IONMANGANESE (II) ION
7
4
SULFATE IONSULFATE ION
8
2
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303