8PYW: Crystal structure of the human Nucleoside-diphosphate kinase B domain bound to compound diphosphate form of AT-9052-Sp

PDB ID: 8PYWDownload
MMDB ID: 240622
PDB Deposition Date: 2023/7/26
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.553  Å
Source Organism:
Similar Structures:
Biological Unit for 8PYW: hexameric; determined by author and by software (PISA)
Molecular Components in 8PYW
Label Count Molecule
Proteins (6 molecules)
6
Nucleoside Diphosphate Kinase B
(Gene symbol: NME2)
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
3
GLYCEROLGLYCEROL
2
6
[[(2R,3R,4R,5R)-5-(2-azanyl-6-oxidanylidene-1H-purin-9-yl)-4-fluoranyl-4-methyl-3-oxidanyl-oxolan-2-yl]methoxy-sulfanyl-phosphoryl] dihydrogen phosphate[[(2R,3R,4R,5R)-5-(2-azanyl-6-oxidanylidene-1H-purin-9-yl)-4-fluoranyl-4-methyl-3-oxidanyl-oxolan-2-yl]methoxy-sulfanyl-phosphoryl] dihydrogen phosphate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303