8PYL: Human IGF1R with inhibitor 53

PDB ID: 8PYLDownload
MMDB ID: 235921
PDB Deposition Date: 2023/7/25
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 2.93  Å
Source Organism:
Similar Structures:
Biological Unit for 8PYL: monomeric; determined by author and by software (PISA)
Molecular Components in 8PYL
Label Count Molecule
Protein (1 molecule)
1
Insulin-like Growth Factor 1 Receptor Beta Chain
(Gene symbol: IGF1R)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
(5S)-5-methyl-1-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)-3-[4-(trifluoromethylsulfanyl)phenyl]imidazolidine-2,4-dione(5S)-5-methyl-1-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)-3-[4-(trifluoromethylsulfanyl)phenyl]imidazolidine-2,4-dione
2
1
NICKEL (II) IONNICKEL (II) ION
3
1
CADMIUM IONCADMIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303