National Center for
Biotechnology Information

8PY4: ABCG2 in complex with ko143 and 5D3 Fab

PDB ID:

MMDB ID:

254499

PDB Deposition Date:

2023/7/25

Updated in MMDB:

2024/11

Experimental Method:

electron microscopy

Resolution:

3 Å

Source Organism:

Mus musculus▼

Taxonomy	Molecule
Mus musculus	D, E, F, C
Homo sapiens	B, A

Similar Structures:

Biological Unit for 8PY4: hexameric; determined by author and by software (PISA)

Molecular Components in 8PY4
Label	Count	Molecule
Proteins (6 molecules)
D F	2	5d3(fab) Heavy Chain Variable Domain
E C	2	5d3(fab) Light Chain Variable Domain
B A	2	Broad Substrate Specificity Atp-binding Cassette Transporter Abcg2
Chemicals and Non-standard biopolymers (16 molecules)
1	4	2-acetamido-2-deoxy-beta-D-glucopyranose
2	10	CHOLESTEROL
3	2	tert-butyl 3-[(2S,5S,8S)-14-methoxy-2-(2-methylpropyl)-4,7-bis(oxidanylidene)-3,6,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,16}]heptadeca-1(10),11,13,15-tetraen-5-yl]propanoate $tert-butyl 3-[(2S,5S,8S)-14-methoxy-2-(2-methylpropyl)-4,7-bis(oxidanylidene)-3,6,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,16}]heptadeca-1(10),11,13,15-tetraen-5-yl]propanoate$

* Click molecule labels to explore molecular sequence information.

Citing MMDB