National Center for
Biotechnology Information

8PXO: ABCG2 in complex with AZ99 and 5D3 Fab

PDB ID:

MMDB ID:

254498

PDB Deposition Date:

2023/7/23

Updated in MMDB:

2024/11

Experimental Method:

electron microscopy

Resolution:

3 Å

Source Organism:

Mus musculus▼

Taxonomy	Molecule
Mus musculus	D, E, F, C
Homo sapiens	B, A

Similar Structures:

Biological Unit for 8PXO: hexameric; determined by author

Molecular Components in 8PXO
Label	Count	Molecule
Proteins (6 molecules)
D F	2	5d3(fab) Heavy Chain Variable Domain\|mus Musculus
E C	2	5d3(fab) Light Chain Variable Domain
B A	2	Broad Substrate Specificity Atp-binding Cassette Transporter Abcg2
Chemicals and Non-standard biopolymers (10 molecules)
1	4	2-acetamido-2-deoxy-beta-D-glucopyranose
2	4	CHOLESTEROL
3	2	(2S,5S,8S)-14-cyclopentyloxy-2-(2-methylpropyl)-5-(phenylmethyl)-3,6,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,16}]heptadeca-1(10),11,13,15-tetraene-4,7-dione $(2S,5S,8S)-14-cyclopentyloxy-2-(2-methylpropyl)-5-(phenylmethyl)-3,6,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,16}]heptadeca-1(10),11,13,15-tetraene-4,7-dione$

* Click molecule labels to explore molecular sequence information.

Citing MMDB