8PTT: Human NUDT5 in complex with MRK-952

PDB ID: 8PTTDownload
MMDB ID: 250065
PDB Deposition Date: 2023/7/14
Updated in MMDB: 2024/07
Experimental Method:
x-ray diffraction
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 8PTT: dimeric; determined by author
Molecular Components in 8PTT
Label Count Molecule
Proteins (2 molecules)
2
Adp-sugar Pyrophosphatase
(Gene symbol: NUDT5)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
6-[(5~{R})-7-[3-chloranyl-4-(trifluoromethyl)phenyl]-2,7-diazaspiro[4.4]nonan-2-yl]-7-methyl-purine6-[(5~{R})-7-[3-chloranyl-4-(trifluoromethyl)phenyl]-2,7-diazaspiro[4.4]nonan-2-yl]-7-methyl-purine
2
4
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303