8PTA: JNK1 covalently bound to BD837 cyclohexenone based inhibitor

PDB ID: 8PTADownload
MMDB ID: 250061
PDB Deposition Date: 2023/7/13
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.41  Å
Source Organism:
Similar Structures:
Biological Unit for 8PTA: monomeric; determined by author
Molecular Components in 8PTA
Label Count Molecule
Protein (1 molecule)
1
Mitogen-activated Protein Kinase 8
(Gene symbol: MAPK8)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
methyl (1R,3S)-1-methyl-3-[[3-[[3-methyl-4-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]carbamoyl]phenyl]carbamoyl]-4-oxidanylidene-cyclohexane-1-carboxylatemethyl (1R,3S)-1-methyl-3-[[3-[[3-methyl-4-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]carbamoyl]phenyl]carbamoyl]-4-oxidanylidene-cyclohexane-1-carboxylate
2
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303