8PQH: PDGFRA T674I mutant kinase domain in complex with avapritinib

PDB ID: 8PQHDownload
MMDB ID: 240607
PDB Deposition Date: 2023/7/11
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 8PQH: monomeric; determined by author
Molecular Components in 8PQH
Label Count Molecule
Protein (1 molecule)
1
Platelet-derived Growth Factor Receptor Alpha
(Gene symbol: PDGFRA)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
AvapritinibAvapritinib
2
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303