8PPE: Human inositol 1,4,5-trisphosphate 3-kinase A (IP3K) catalytic domain in complex with DL-6-deoxy-6-phosphoryloxymethyl-scyllo-inositol 1,2,4-trisphosphate/ADP/Mn

PDB ID: 8PPEDownload
MMDB ID: 243331
PDB Deposition Date: 2023/7/7
Updated in MMDB: 2024/04
Experimental Method:
x-ray diffraction
Resolution: 1.59  Å
Source Organism:
Similar Structures:
Biological Unit for 8PPE: monomeric; determined by author
Molecular Components in 8PPE
Label Count Molecule
Protein (1 molecule)
1
Inositol-trisphosphate 3-kinase a
(Gene symbol: ITPKA)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
ADENOSINE-5'-DIPHOSPHATEADENOSINE-5'-DIPHOSPHATE
2
1
DL-6-deoxy-6-phosphoryloxymethyl-scyllo-inositol 1,2,4-trisphosphateDL-6-deoxy-6-phosphoryloxymethyl-scyllo-inositol 1,2,4-trisphosphate
3
1
GLYCEROLGLYCEROL
4
1
MANGANESE (II) IONMANGANESE (II) ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303