8PP0: Crystal structure of Retinoic Acid Receptor alpha (RXRA) in complexed with JP147

PDB ID: 8PP0Download
MMDB ID: 242350
PDB Deposition Date: 2023/7/5
Updated in MMDB: 2024/02
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 8PP0: dimeric; determined by author and by software (PISA)
Molecular Components in 8PP0
Label Count Molecule
Proteins (2 molecules)
1
Retinoic Acid Receptor Rxr-alpha
(Gene symbol: RXRA)
Molecule annotation
1
Nuclear Receptor Coactivator 2
(Gene symbol: NCOA2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
3-[4-[2,3-dihydro-1H-inden-4-yl(methyl)amino]-6-(trifluoromethyl)pyrimidin-2-yl]oxypropanoic acid3-[4-[2,3-dihydro-1H-inden-4-yl(methyl)amino]-6-(trifluoromethyl)pyrimidin-2-yl]oxypropanoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303