8POD: Crystal structure of the kinase domain of ACVR1 (ALK2) in complex with FKBP12 and MU1700

PDB ID: 8PODDownload
MMDB ID: 248470
PDB Deposition Date: 2023/7/4
Updated in MMDB: 2024/06
Experimental Method:
x-ray diffraction
Resolution: 2.59  Å
Source Organism:
Similar Structures:
Biological Unit for 8POD: dimeric; determined by author and by software (PISA)
Molecular Components in 8POD
Label Count Molecule
Proteins (2 molecules)
1
Activin Receptor Type-1
(Gene symbol: ACVR1)
Molecule annotation
1
Peptidyl-prolyl Cis-trans Isomerase Fkbp1a
(Gene symbol: FKBP1A)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
6-(4-piperazin-1-ylphenyl)-3-quinolin-4-yl-furo[3,2-b]pyridine6-(4-piperazin-1-ylphenyl)-3-quinolin-4-yl-furo[3,2-b]pyridine
2
1
FLUORIDE IONFLUORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303