8PMO: Crystal structure of human V122I transthyretin in complex with PITB (Pharmacokinetically Improved TTR Binder)

PDB ID: 8PMODownload
MMDB ID: 246450
PDB Deposition Date: 2023/6/29
Updated in MMDB: 2024/05
Experimental Method:
x-ray diffraction
Resolution: 1.24  Å
Source Organism:
Similar Structures:
Biological Unit for 8PMO: tetrameric; determined by author
Molecular Components in 8PMO
Label Count Molecule
Proteins (4 molecules)
4
Transthyretin
(Gene symbol: TTR)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
(3-fluoranyl-5-oxidanyl-phenyl)-(3-methoxy-5-nitro-4-oxidanyl-phenyl)methanone(3-fluoranyl-5-oxidanyl-phenyl)-(3-methoxy-5-nitro-4-oxidanyl-phenyl)methanone
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303