8PK9: Structure of the human mitochondrial iron-sulfur cluster biosynthesis complex during persulfide transfer (persulfide on NFS1 and ISCU2)

PDB ID: 8PK9Download
MMDB ID: 246119
PDB Deposition Date: 2023/6/26
Updated in MMDB: 2024/05
Experimental Method:
electron microscopy
Resolution: 2.58  Å
Source Organism:
Escherichia coli BL21(DE3)▼
Similar Structures:
Biological Unit for 8PK9: pentameric; determined by author and by software
Molecular Components in 8PK9
Label Count Molecule
Proteins (5 molecules)
1
Cysteine Desulfurase
Molecule annotation
1
LYR Motif-containing Protein 4
Molecule annotation
1
Acyl Carrier Protein
Molecule annotation
1
Iron-sulfur Cluster Assembly Enzyme Iscu
Molecule annotation
1
Frataxin Mature Form
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
PYRIDOXAL-5'-PHOSPHATEPYRIDOXAL-5'-PHOSPHATE
2
1
S-[2-({N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioateS-[2-({N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate
3
1
FE (II) IONFE (II) ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303