8PJK: ST171-bound serotonin 5-HT1A receptor - Gi Protein Complex

PDB ID: 8PJKDownload
MMDB ID: 247585
PDB Deposition Date: 2023
Updated in MMDB: 2024/12
Experimental Method:
electron microscopy
Resolution: 2.4  Å
Source Organism:
Similar Structures:
Biological Unit for 8PJK: tetrameric; determined by author
Molecular Components in 8PJK
Label Count Molecule
Proteins (4 molecules)
1
Guanine Nucleotide-binding Protein G(i) Subunit Alpha-1
(Gene symbol: GNAI1)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
(Gene symbol: GNB1)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
(Gene symbol: GNG2)
Molecule annotation
1
5-hydroxytryptamine Receptor 1A
(Gene symbol: HTR1A)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
CHOLESTEROLCHOLESTEROL
2
1
6-[3-[2-(2-methoxyphenoxy)ethylamino]propoxy]-4~{H}-1,4-benzoxazin-3-one6-[3-[2-(2-methoxyphenoxy)ethylamino]propoxy]-4~{H}-1,4-benzoxazin-3-one
3
1
(2R)-1-(heptadecanoyloxy)-3-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate(2R)-1-(heptadecanoyloxy)-3-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303