8PI3: Cathepsin S Y132D mutant in complex with NNPI-C10 inhibitor

PDB ID: 8PI3Download
MMDB ID: 247866
PDB Deposition Date: 2023/6/21
Updated in MMDB: 2024/09
Experimental Method:
x-ray diffraction
Resolution: 1.73  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 8PI3: dimeric; determined by author and by software (PISA)
Molecular Components in 8PI3
Label Count Molecule
Proteins (2 molecules)
1
Cathepsin S
Molecule annotation
1
Nnpi-c10 Inhibitor
Molecule annotation
Chemicals and Non-standard biopolymers (20 molecules)
1
5
CHLORIDE IONCHLORIDE ION
2
1
GLYCEROLGLYCEROL
3
5
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
4
CADMIUM IONCADMIUM ION
5
2
ACETATE IONACETATE ION
6
3
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303