8PF8: Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with Fragment-M-72

PDB ID: 8PF8Download
MMDB ID: 250321
PDB Deposition Date: 2023/6/15
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.23  Å
Source Organism:
Similar Structures:
Biological Unit for 8PF8: tetrameric; determined by author
Molecular Components in 8PF8
Label Count Molecule
Proteins (4 molecules)
2
Probable Fatty Oxidation Protein Fadb
(Gene symbol: fadB)
Molecule annotation
2
Putative Acyltransferase Rv0859
(Gene symbol: Rv0859)
Molecule annotation
Chemicals and Non-standard biopolymers (35 molecules)
1
23
SULFATE IONSULFATE ION
2
1
GLYCEROLGLYCEROL
3
1
(2~{R})-3-bis[2-methyl-5-(trifluoromethyl)pyrazol-3-yl]boranyloxypropane-1,2-diol(2~{R})-3-bis[2-methyl-5-(trifluoromethyl)pyrazol-3-yl]boranyloxypropane-1,2-diol
4
2
[(2~{R})-2,3-bis(oxidanyl)propoxy]-[2-methyl-5-(trifluoromethyl)pyrazol-3-yl]borinic acid[(2~{R})-2,3-bis(oxidanyl)propoxy]-[2-methyl-5-(trifluoromethyl)pyrazol-3-yl]borinic acid
5
2
bis[2-methyl-5-(trifluoromethyl)pyrazol-3-yl]-bis(oxidanyl)boranuidebis[2-methyl-5-(trifluoromethyl)pyrazol-3-yl]-bis(oxidanyl)boranuide
6
6
[2-methyl-5-(trifluoromethyl)pyrazol-3-yl]boronic acid[2-methyl-5-(trifluoromethyl)pyrazol-3-yl]boronic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303