8PEM: Zika Methyltransferase in complex with AT-9010 and SAH

PDB ID: 8PEMDownload
MMDB ID: 275942
PDB Deposition Date: 2023/6/14
Updated in MMDB: 2026/01
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 8PEM: monomeric; determined by author and by software (PISA)
Molecular Components in 8PEM
Label Count Molecule
Protein (1 molecule)
1
RNA-directed RNA Polymerase NS5
(Gene symbol: POLY)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
[[(2R,3R,4R,5R)-5-(2-azanyl-6-oxidanylidene-1H-purin-9-yl)-4-fluoranyl-4-methyl-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate[[(2R,3R,4R,5R)-5-(2-azanyl-6-oxidanylidene-1H-purin-9-yl)-4-fluoranyl-4-methyl-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate
2
1
S-ADENOSYL-L-HOMOCYSTEINES-ADENOSYL-L-HOMOCYSTEINE
3
1
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303