8P5L: Kinase domain of mutant human ULK1 in complex with compound MRT67307

PDB ID: 8P5LDownload
MMDB ID: 247864
PDB Deposition Date: 2023/5/24
Updated in MMDB: 2024/06
Experimental Method:
x-ray diffraction
Resolution: 1.836  Å
Source Organism:
Similar Structures:
Biological Unit for 8P5L: monomeric; determined by author
Molecular Components in 8P5L
Label Count Molecule
Protein (1 molecule)
1
Serine/threonine-protein Kinase Ulk1
(Gene symbol: ULK1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
N-{3-[(5-cyclopropyl-2-{[3-(morpholin-4-ylmethyl)phenyl]amino}pyrimidin-4-yl)amino]propyl}cyclobutanecarboxamideN-{3-[(5-cyclopropyl-2-{[3-(morpholin-4-ylmethyl)phenyl]amino}pyrimidin-4-yl)amino]propyl}cyclobutanecarboxamide
2
2
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303