8P3I: Fusion hSlp2-a_Rab27A bound to covalent hit fragment IMP-1721

PDB ID: 8P3IDownload
MMDB ID: 255191
PDB Deposition Date: 2023/5/17
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 8P3I: dimeric; determined by author and by software (PISA)
Molecular Components in 8P3I
Label Count Molecule
Proteins (2 molecules)
2
Synaptotagmin-like Protein 2,ras-related Protein Rab-27a
(Gene symbol: RAB27A)
Molecule annotation
Chemicals and Non-standard biopolymers (18 molecules)
1
2
PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTERPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
2
12
GLYCEROLGLYCEROL
3
2
~{N}-(3-methoxy-4-pyrrolidin-1-ylsulfonyl-phenyl)propanamide~{N}-(3-methoxy-4-pyrrolidin-1-ylsulfonyl-phenyl)propanamide
4
2
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303