8P3E: Crystal structure of glucocerebrosidase in complex with allosteric activator

PDB ID: 8P3EDownload
MMDB ID: 243665
PDB Deposition Date: 2023/5/17
Updated in MMDB: 2024/05
Experimental Method:
x-ray diffraction
Resolution: 1.75  Å
Source Organism:
Similar Structures:
Biological Unit for 8P3E: tetrameric; determined by software (PISA)
Molecular Components in 8P3E
Label Count Molecule
Proteins (4 molecules)
4
Glucosylceramidase
(Gene symbol: GBA)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
8
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
2
2-[[3-[(4-chlorophenyl)carbamoyl]phenyl]sulfonylamino]benzoic acid2-[[3-[(4-chlorophenyl)carbamoyl]phenyl]sulfonylamino]benzoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303