8P0M: Crystal structure of TEAD3 in complex with IAG933

PDB ID: 8P0MDownload
MMDB ID: 245200
PDB Deposition Date: 2023/5/10
Updated in MMDB: 2024/08
Experimental Method:
x-ray diffraction
Resolution: 1.961  Å
Source Organism:
Similar Structures:
Biological Unit for 8P0M: tetrameric; determined by author
Molecular Components in 8P0M
Label Count Molecule
Proteins (4 molecules)
2
Transcriptional Enhancer Factor Tef-5
(Gene symbol: TEAD3)
Molecule annotation
2
Transcriptional Enhancer Factor Tef-5
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
3
2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL
2
2
MYRISTIC ACIDMYRISTIC ACID
3
4
4-[(2~{S})-5-chloranyl-6-fluoranyl-2-phenyl-2-[(2~{S})-pyrrolidin-2-yl]-3~{H}-1-benzofuran-4-yl]-5-fluoranyl-6-(2-hydroxyethyloxy)-~{N}-methyl-pyridine-3-carboxamide4-[(2~{S})-5-chloranyl-6-fluoranyl-2-phenyl-2-[(2~{S})-pyrrolidin-2-yl]-3~{H}-1-benzofuran-4-yl]-5-fluoranyl-6-(2-hydroxyethyloxy)-~{N}-methyl-pyridine-3-carboxamide
4
2
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303