8P0I: Crystal structure of the open conformation of insulin-regulated aminopeptidase in complex with a small-MW inhibitor

PDB ID: 8P0IDownload
MMDB ID: 251668
PDB Deposition Date: 2023/5/10
Updated in MMDB: 2024/09
Experimental Method:
x-ray diffraction
Resolution: 3.5  Å
Source Organism:
Similar Structures:
Biological Unit for 8P0I: monomeric; determined by author
Molecular Components in 8P0I
Label Count Molecule
Protein (1 molecule)
1
Leucyl-cystinyl Aminopeptidase, Pregnancy Serum Form
(Gene symbol: LNPEP)
Molecule annotation
Chemicals and Non-standard biopolymers (17 molecules)
1
15
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
2-[2-(3,5-dimethylpyrazol-1-yl)-6-(4-methoxyphenyl)pyrimidin-4-yl]oxy-N-methyl-N-[(2-methylpyridin-3-yl)methyl]ethanamide2-[2-(3,5-dimethylpyrazol-1-yl)-6-(4-methoxyphenyl)pyrimidin-4-yl]oxy-N-methyl-N-[(2-methylpyridin-3-yl)methyl]ethanamide
3
1
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303