8P08: Crystal structure of human CLK1 in complex with Leucettinib-21

PDB ID: 8P08Download
MMDB ID: 230345
PDB Deposition Date: 2023/5/9
Updated in MMDB: 2024/08
Experimental Method:
x-ray diffraction
Resolution: 2.4  Å
Source Organism:
Similar Structures:
Biological Unit for 8P08: monomeric; determined by author
Molecular Components in 8P08
Label Count Molecule
Protein (1 molecule)
1
Dual Specificity Protein Kinase Clk1
(Gene symbol: CLK1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(4~{Z})-4-(1,3-benzothiazol-6-ylmethylidene)-2-[[(2~{R})-1-methoxy-4-methyl-pentan-2-yl]amino]-1~{H}-imidazol-5-one(4~{Z})-4-(1,3-benzothiazol-6-ylmethylidene)-2-[[(2~{R})-1-methoxy-4-methyl-pentan-2-yl]amino]-1~{H}-imidazol-5-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303