8OXX: Transglutaminase 3 in complex with inhibitor Z-don and DH patient-derived Fab DH63-B02

PDB ID: 8OXXDownload
MMDB ID: 236929
PDB Deposition Date: 2023/5/2
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 8OXX: trimeric; determined by author
Molecular Components in 8OXX
Label Count Molecule
Proteins (3 molecules)
1
Protein-glutamine Gamma-glutamyltransferase E 27 KDA Non-catalytic Chain
(Gene symbol: TGM3)
Molecule annotation
1
Antibody FAB Fragment Heavy Chain
Molecule annotation
1
Antibody FAB Fragment Light Chain
Molecule annotation
Chemicals and Non-standard biopolymers (15 molecules)
1
1
SULFATE IONSULFATE ION
2
6
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
3
CALCIUM IONCALCIUM ION
4
1
benzyl hydrogen carbonatebenzyl hydrogen carbonate
5
1
5-OXO-L-NORLEUCINE5-OXO-L-NORLEUCINE
6
1
D-VALINED-VALINE
7
1
D-PROLINED-PROLINE
8
1
METHYL L-LEUCINATEMETHYL L-LEUCINATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303