8OW2: Crystal structure of the p110alpha catalytic subunit from homo sapiens in complex with activator 1938

PDB ID: 8OW2Download
MMDB ID: 230660
PDB Deposition Date: 2023/4/26
Updated in MMDB: 2024/06
Experimental Method:
x-ray diffraction
Resolution: 2.57  Å
Source Organism:
Similar Structures:
Biological Unit for 8OW2: monomeric; determined by author and by software (PISA)
Molecular Components in 8OW2
Label Count Molecule
Protein (1 molecule)
1
Phosphatidylinositol 4,5-bisphosphate 3-kinase Catalytic Subunit Alpha Isoform
(Gene symbol: PIK3CA)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
1-[7-[[2-[[4-(4-ethylpiperazin-1-yl)phenyl]amino]pyridin-4-yl]amino]-2,3-dihydroindol-1-yl]ethanone1-[7-[[2-[[4-(4-ethylpiperazin-1-yl)phenyl]amino]pyridin-4-yl]amino]-2,3-dihydroindol-1-yl]ethanone
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303