8OU5: Cereblon isoform 4 in complex with novel Benzamide-Type Cereblon Binder 11b

PDB ID: 8OU5Download
MMDB ID: 238536
PDB Deposition Date: 2023/4/21
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 8OU5: trimeric; determined by author
Molecular Components in 8OU5
Label Count Molecule
Proteins (3 molecules)
3
Cereblon Isoform 4
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
3
ZINC IONZINC ION
2
2
4-azanyl-~{N}-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-2-(trifluoromethyl)benzamide4-azanyl-~{N}-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-2-(trifluoromethyl)benzamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303