8OQA: CryoEM structure of human rho1 GABAA receptor in complex with GABA and picrotoxin

PDB ID: 8OQADownload
MMDB ID: 234871
PDB Deposition Date: 2023/4/11
Updated in MMDB: 2023/11
Experimental Method:
electron microscopy
Resolution: 2.9  Å
Source Organism:
Similar Structures:
Biological Unit for 8OQA: pentameric; determined by author
Molecular Components in 8OQA
Label Count Molecule
Proteins (5 molecules)
5
Gamma-aminobutyric Acid Receptor Subunit Rho-1
(Gene symbol: GABRR1)
Molecule annotation
Chemicals and Non-standard biopolymers (36 molecules)
1
10
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
14
HEXANEHEXANE
3
4
N-OCTANEN-OCTANE
4
2
CHLORIDE IONCHLORIDE ION
5
5
GAMMA-AMINO-BUTANOIC ACIDGAMMA-AMINO-BUTANOIC ACID
6
1
(1aR,2aR,3S,6R,6aS,8aS,8bR,9R)-2a-hydroxy-8b-methyl-9-(prop-1-en-2-yl)hexahydro-3,6-methano-1,5,7-trioxacyclopenta[ij]c yclopropa[a]azulene-4,8(3H)-dione(1aR,2aR,3S,6R,6aS,8aS,8bR,9R)-2a-hydroxy-8b-methyl-9-(prop-1-en-2-yl)hexahydro-3,6-methano-1,5,7-trioxacyclopenta[ij]c yclopropa[a]azulene-4,8(3H)-dione
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303