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8ONV:
KRAS-G13D in complex with BI-2493
PDB ID:
8ONV
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MMDB ID:
231236
PDB Deposition Date:
2023/4/4
Updated in MMDB:
2023/07
Experimental Method:
x-ray diffraction
Resolution:
1.01 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 8ONV: monomeric; determined by author
Molecular Components in 8ONV
Label
Count
Molecule
Protein (1 molecule)
A
1
Gtpase Kras
(Gene symbol:
KRAS
)
Chemicals and Non-standard biopolymers (5 molecules)
1
1
GUANOSINE-5'-DIPHOSPHATE
2
1
MAGNESIUM ION
3
2
1,2-ETHANEDIOL
4
1
(7~{S})-2'-azanyl-3-[2-[(2~{S})-2-methylpiperazin-1-yl]pyrimidin-4-yl]spiro[5,6-dihydro-4~{H}-1,2-benzoxazole-7,4'-6,7-dihydro-5~{H}-1-benzothiophene]-3'-carbonitrile
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303