8ONV: KRAS-G13D in complex with BI-2493

PDB ID: 8ONVDownload
MMDB ID: 231236
PDB Deposition Date: 2023/4/4
Updated in MMDB: 2023/07
Experimental Method:
x-ray diffraction
Resolution: 1.01  Å
Source Organism:
Similar Structures:
Biological Unit for 8ONV: monomeric; determined by author
Molecular Components in 8ONV
Label Count Molecule
Protein (1 molecule)
1
Gtpase Kras
(Gene symbol: KRAS)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
GUANOSINE-5'-DIPHOSPHATEGUANOSINE-5'-DIPHOSPHATE
2
1
MAGNESIUM IONMAGNESIUM ION
3
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
1
(7~{S})-2'-azanyl-3-[2-[(2~{S})-2-methylpiperazin-1-yl]pyrimidin-4-yl]spiro[5,6-dihydro-4~{H}-1,2-benzoxazole-7,4'-6,7-dihydro-5~{H}-1-benzothiophene]-3'-carbonitrile(7~{S})-2'-azanyl-3-[2-[(2~{S})-2-methylpiperazin-1-yl]pyrimidin-4-yl]spiro[5,6-dihydro-4~{H}-1,2-benzoxazole-7,4'-6,7-dihydro-5~{H}-1-benzothiophene]-3'-carbonitrile
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303