8OMJ: hKHK-C in complex with compound 28

PDB ID: 8OMJDownload
MMDB ID: 249462
PDB Deposition Date: 2023/3/31
Updated in MMDB: 2024/09
Experimental Method:
x-ray diffraction
Resolution: 1.978  Å
Source Organism:
Similar Structures:
Biological Unit for 8OMJ: dimeric; determined by author
Molecular Components in 8OMJ
Label Count Molecule
Proteins (2 molecules)
2
Ketohexokinase
(Gene symbol: KHK)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
[3-[[6-[(3~{a}~{R},6~{a}~{S})-2,3,3~{a},4,6,6~{a}-hexahydro-1~{H}-pyrrolo[3,4-c]pyrrol-5-yl]-3-cyano-4-(trifluoromethyl)pyridin-2-yl]amino]-4-methylsulfanyl-phenyl]methoxy-methyl-phosphinic acid[3-[[6-[(3~{a}~{R},6~{a}~{S})-2,3,3~{a},4,6,6~{a}-hexahydro-1~{H}-pyrrolo[3,4-c]pyrrol-5-yl]-3-cyano-4-(trifluoromethyl)pyridin-2-yl]amino]-4-methylsulfanyl-phenyl]methoxy-methyl-phosphinic acid
2
2
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303