8OJH: Crystal structure of human CRBN-DDB1 in complex with compound 4

PDB ID: 8OJHDownload
MMDB ID: 233107
PDB Deposition Date: 2023/3/24
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.72  Å
Source Organism:
Similar Structures:
Biological Unit for 8OJH: dimeric; determined by author
Molecular Components in 8OJH
Label Count Molecule
Proteins (2 molecules)
1
DNA Damage-binding Protein 1
(Gene symbol: DDB1)
Molecule annotation
1
Protein Cereblon
(Gene symbol: CRBN)
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
9
1,2-ETHANEDIOL1,2-ETHANEDIOL
2
1
ZINC IONZINC ION
3
1
4-azanyl-2-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-7-methoxy-isoindole-1,3-dione4-azanyl-2-[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]-7-methoxy-isoindole-1,3-dione
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303