8OIZ: Crystal structure of human CRBN-DDB1 in complex with Pomalidomide

PDB ID: 8OIZDownload
MMDB ID: 233106
PDB Deposition Date: 2023/3/23
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 8OIZ: dimeric; determined by author and by software (PISA)
Molecular Components in 8OIZ
Label Count Molecule
Proteins (2 molecules)
1
DNA Damage-binding Protein 1
(Gene symbol: DDB1)
Molecule annotation
1
Protein Cereblon
(Gene symbol: CRBN)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
6
1,2-ETHANEDIOL1,2-ETHANEDIOL
2
1
ZINC IONZINC ION
3
1
S-PomalidomideS-Pomalidomide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303