8OGA: Crystal structure of human DCAF1 WD40 repeats (Q1250L) in complex with compound 6

PDB ID: 8OGADownload
MMDB ID: 231771
PDB Deposition Date: 2023/3/19
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 8OGA: monomeric; determined by author
Molecular Components in 8OGA
Label Count Molecule
Protein (1 molecule)
1
Ddb1- and Cul4-associated Factor 1
(Gene symbol: DCAF1)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
3
1,2-ETHANEDIOL1,2-ETHANEDIOL
2
2
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
3
1
5-[1-(4-methoxyphenyl)cyclopropyl]-8-(4-methylpiperazin-1-yl)-2,3-dihydroimidazo[2,1-a]isoquinoline5-[1-(4-methoxyphenyl)cyclopropyl]-8-(4-methylpiperazin-1-yl)-2,3-dihydroimidazo[2,1-a]isoquinoline
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303