8OFA: Crystal structure of human cathepsin L interacting with tosyl phenylalanyl chloromethyl ketone (TPCK)

PDB ID: 8OFADownload
MMDB ID: 239188
PDB Deposition Date: 2023/3/14
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 8OFA: monomeric; determined by author
Molecular Components in 8OFA
Label Count Molecule
Protein (1 molecule)
1
Cathepsin L
(Gene symbol: CTSL)
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
1
N-[(2S)-4-chloro-3-oxo-1-phenyl-butan-2-yl]-4-methyl-benzenesulfonamideN-[(2S)-4-chloro-3-oxo-1-phenyl-butan-2-yl]-4-methyl-benzenesulfonamide
2
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
2
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
4
4
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
5
1
TRIETHYLENE GLYCOLTRIETHYLENE GLYCOL
6
1
1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE
7
1
4-methyl-~{N}-[(2~{S})-4-oxidanyl-3-oxidanylidene-1-phenyl-butan-2-yl]benzenesulfonamide4-methyl-~{N}-[(2~{S})-4-oxidanyl-3-oxidanylidene-1-phenyl-butan-2-yl]benzenesulfonamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303