8OF5: Crystal structure of Aurora A 122-403 C290A, N332A, Q335A, C393A bound to ADP

PDB ID: 8OF5Download
MMDB ID: 244575
PDB Deposition Date: 2023/3/14
Updated in MMDB: 2024/04
Experimental Method:
x-ray diffraction
Resolution: 1.97  Å
Source Organism:
Similar Structures:
Biological Unit for 8OF5: dimeric; determined by software (PISA)
Molecular Components in 8OF5
Label Count Molecule
Proteins (2 molecules)
2
Aurora Kinase a
(Gene symbol: AURKA)
Molecule annotation
Chemicals and Non-standard biopolymers (18 molecules)
1
2
ADENOSINE-5'-DIPHOSPHATEADENOSINE-5'-DIPHOSPHATE
2
2
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
3
4
GLYCEROLGLYCEROL
4
2
3[N-MORPHOLINO]PROPANE SULFONIC ACID3[N-MORPHOLINO]PROPANE SULFONIC ACID
5
2
NITRATE IONNITRATE ION
6
6
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303