8KI3: Structure of the human ATP synthase bound to bedaquiline (composite)

PDB ID: 8KI3Download
MMDB ID: 246085
PDB Deposition Date: 2023/8/22
Updated in MMDB: 2024/08
Experimental Method:
electron microscopy
Resolution: 2.89  Å
Source Organism:
Similar Structures:
Biological Unit for 8KI3: 28-meric; determined by author
Molecular Components in 8KI3
Label Count Molecule
Proteins (28 molecules)
3
ATP Synthase Subunit Alpha, Mitochondrial
(Gene symbol: ATP5F1A)
Molecule annotation
3
ATP Synthase Subunit Beta, Mitochondrial
(Gene symbol: ATP5F1B)
Molecule annotation
1
ATP Synthase Subunit Gamma, Mitochondrial
(Gene symbol: ATP5F1C)
Molecule annotation
1
Atpase Inhibitor, Mitochondrial
(Gene symbol: ATP5IF1)
Molecule annotation
1
ATP Synthase Subunit O, Mitochondrial
(Gene symbol: ATP5PO)
Molecule annotation
8
ATP Synthase F(0) Complex Subunit C1, Mitochondrial
(Gene symbol: ATP5MC1)
Molecule annotation
1
ATP Synthase Subunit Delta, Mitochondrial
(Gene symbol: ATP5F1D)
Molecule annotation
1
ATP Synthase Subunit Epsilon, Mitochondrial
(Gene symbol: ATP5F1E)
Molecule annotation
1
ATP Synthase F(0) Complex Subunit B1, Mitochondrial
(Gene symbol: ATP5PB)
Molecule annotation
1
ATP Synthase Subunit D, Mitochondrial
(Gene symbol: ATP5PD)
Molecule annotation
1
ATP Synthase Subunit a
(Gene symbol: ATP6)
Molecule annotation
1
ATP Synthase Subunit Atp5mj, Mitochondrial
(Gene symbol: ATP5MPL)
Molecule annotation
1
ATP Synthase Protein 8
(Gene symbol: ATP8)
Molecule annotation
1
ATP Synthase Subunit F, Mitochondrial
(Gene symbol: ATP5MF)
Molecule annotation
1
ATP Synthase Subunit G, Mitochondrial
(Gene symbol: ATP5MG)
Molecule annotation
1
ATP Synthase Subunit E, Mitochondrial
(Gene symbol: ATP5ME)
Molecule annotation
1
ATP Synthase-coupling Factor 6, Mitochondrial
(Gene symbol: ATP5PF)
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
3
ADENOSINE-5'-TRIPHOSPHATEADENOSINE-5'-TRIPHOSPHATE
2
5
MAGNESIUM IONMAGNESIUM ION
3
2
ADENOSINE-5'-DIPHOSPHATEADENOSINE-5'-DIPHOSPHATE
4
1
BedaquilineBedaquiline
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303